Gas source isotope ratio mass spectrometry

Gas source isotope ratio mass spectrometry, or IRMS, is a technique widely used in the Earth sciences, environmental sciences, and a diverse range of other applications including anti-doping and food adulteration determination. Although this is now a routine tool, there remain some applications where the measurement precision of the analytical instrument can limit the science.


The study of isotopologues, or clumped isotopes, has proved in recent years to be scientifically valuable. For example, isotopologues of CO2 can be used along with other factors to determine paleoclimate information that can help our understanding of long-term climate change. However, this study of the isotopes of carbon dioxide can be challenging. The isotopologues at m/z 48 and 49 are of low abundance. In some instruments there are also high instrument backgrounds in this region of the mass spectrum, making an accurate and precise measurement impossible.


By using the proven large-radius ion optical system of our Phoenix TIMS we have been able to alleviate some of these difficulties and our resulting solution, SIRIX, is able to measure these challenging isotopes more precisely than many existing IRMS instruments.

SIRIX Brochure Download

ISO 9001


Isotopx Ltd
Dalton House,
Dalton Way,
Middlewich, Cheshire,
United Kingdom,
CW10 0HU


Tel: +44 (0) 1606 839810
Fax: +44 (0) 1606 839811

Registered in England No: 6447777.
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